Exploring Native Mass Spectrometry: The Key to Next-Level Molecular Characterization
In the world of molecular research, accurately understanding the structure and behavior of biological molecules is paramount. Native Mass Spectrometry (MS) has emerged as a revolutionary technique that enables researchers to study biomolecules in their natural, intact form. Unlike traditional mass spectrometry, which often requires molecules to be fragmented or altered, native mass spectrometry preserves the biological integrity of molecules while providing high-resolution insights into their structure, interactions, and functions. This ability to characterize molecules at the highest level has made native MS an indispensable tool across a wide range of scientific disciplines, from drug discovery to biotechnology. What is Native Mass Spectrometry? Native mass spectrometry is a form of mass spectrometry that analyzes molecules in their native, biologically relevant state . Unlike conventional mass spectrometry, which typically requires molecules to be denatured or broken down into sma